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Heres an example: you feel perfectly fine and physically comfortable until you suddenly get stressed about something at work or a personal problem, and then instantly, a raging hot flash erupts

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For instance, both semaglutide and some antidepressants (particularly SSRIs or SNRIs) can cause gastrointestinal issues such as nausea or diarrhea, which may intensify when taken together. GLP-1s and depression Experts continue to explore the potential effect that taking a medication like semaglutide could have on your mental health